Archive for the ‘Pain Relief/Muscle Relaxant’ Category

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Zanaflex (Tizanidine)
PHYSICAL METHODS TO TREAT MIGRAINE: COUNTER-IRRITATION AND MANIPULATION
Counter-irritation
Similar in effect to acupuncture are various techniques which employ counter-irritation of the painful area. Some techniques use vibration and the patient stimulates the painful area for a few minutes each day. The efficacy of these techniques has yet to be assessed, particularly as they carry a potent placebo effect.
Manipulation
Manipulation of the spine, which may help backache, has been tried on patients with migraine, on the premise that the pain which arises at the back of the neck is brought about by malfunction of the cervical spine. No controlled trials have been done and the theoretical basis for this treatment is not scientifically proven.
Osteopathy is also based on spinal manipulation. Osteopaths ascribe a whole host of disorders to bad posture, e.g. disorders of digestion. Osteopaths are not recognized as medical practitioners in the U.K. by the General Medical Council, although in the United States their position is more accepted. Many medical schools there have recognized departments of osteopathy, and the course of studies is similar in length and content to that required for a medical degree.
Although many of the claims for efficacy of manipulation are exaggerated, it has a place in treatment of certain conditions of the neck producing headache, by relieving muscle tension. Care must be taken because there are two vertebral arteries which run through the spine in the neck to supply the base of the brain; manipulation can lead to the blockage of these vessels causing a stroke.
Although many migraine patients claim to have had relief by osteopathic treatment, there is no clear-cut proof that this method has any higher percentage success rate than would be expected from the placebo response.
*49/152/5*

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CLUSTER HEADACHES: THE CLUSTER HEADACHE PROFILE
The Cluster Headache Profile below is a description of the symptoms of cluster headaches. It is followed by a series of questions that a physician might ask you if cluster headaches were suspected as the diagnosis.
Warning: This exercise is not a means of diagnosing your headaches. The exercise is provided only to encourage you to carefully consider the features of your own headaches using a characterization of cluster headaches for comparison. An accurate diagnosis of your headache problem requires a thorough evaluation by a trained professional. There is no acceptable substitute.
Profile-You have recurring headaches on one side of your face; your eye and jaw on that side are also involved. The headaches occur in episodes lasting fifteen minutes to an hour each. The attacks can occur one to six times during the day and night and tend to repeat in bouts that last for weeks or months. You may go for months or even years without a recurrence.
During an attack, you may experience, on the affected side of your face, a runny nose, tearing, and a bloodshot eye. You do not have a warning that an attack will occur. Your attacks often come during the nighttime, awakening you from a sound sleep one or more times. The pain is excruciating. Ingestion of any form of alcoholic beverage almost invariably brings on an attack during one of the bouts.
If this brief and general description of cluster headaches is similar to your headaches, you may want to answer the following questions. The questions are typical of some of those that would be asked of you if your physician suspected a diagnosis of cluster headaches.
True False
1. Your headaches began after the age of twenty.
2. Your attacks occur in groups, or clusters, of at least one to six per day.
3. Each bout of headaches lasts for one to three months at a time.
4. A headache can be brought on by drinking alcohol during a bout of attacks.
5. Between attacks, you are in good health.
6. You are without headaches most of the time except for the cluster period.
7. Your headaches are worsened by bending over.
8. During an attack, your nose, on the same side as the pain, is runny.
9. During an attack, your eye, on the side of the headache, tears or waters.
10. You feel like pacing, running, screaming, or thrusting your fist or head against a wall during a headache.
11. You are a heavy smoker.
12. You are inclined to drink alcohol frequently.
The characterization that you have just read and the questions that have been asked represent a profile of many cluster headaches.
*47/88/2*

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Ultram (Ultram)
FACTORS CAUSING BACK PAIN: ON-THE-JOB RISK AND STRESS
On-the-job Risk
Many experts have found that jobs that require frequent heavy lifting and similar routine duties may have a higher risk of back pain and injuries. If your job is repetitious or tedious and you have had a back injury, you should take special measures to strengthen your back muscles. Be sure to use proper lifting techniques, and take particular care that you do all you can to prevent back injuries. Your employer may be able to contribute to preventing back injuries by providing special safety equipment. Ideally, employers show concern for their workers by giving attention to individual needs in the workplace. Prevention education and evaluation of the job site can also guard against serious injuries.
Workers who feel dissatisfied with their jobs seem to be at higher risk for back pain. This situation may be difficult to deal with, but, if possible, try to eliminate those factors that are contributing to your dissatisfaction. This may be very difficult in I some cases, without a job change.
Stress
Back pain causes stress, and stress from other causes can make the back pain worse. In this vicious cycle of pain and stress, each makes the other worse. Pain caused by stress is not imagined; it is very real. Among the other medical problems that can be made worse by stress are the many types of arthritis.
Stress can disrupt other parts of your life, including the interpersonal relationships in your family and at work. The stress caused by back pain, with its loss of activity, loss of sleep, loss of income, and high expenses, can be devastating. These effects can be attacked and controlled, and steps can be taken to prevent and control stress later.
*49/135/5*

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Other names: Urispas
Tricor (Fenofibrate)
ANGINA AND SELF-HELP
This article concerns the main points of beginning and maintaining a support group. It gives you advice on how to select group leaders and gives a description of the key workers within the group. It covers the role of professional involvement and suggests why you should involve these people in the group. The experiences of the South Birmingham Angina Group, which has been running for three years, is discussed, its successes and failures, its aims and objectives, and a typical year in the Group’s life is charted.
Social support can act as a buffer to stress. Self-help groups are one form of this buffer. They allow people who are experiencing the disease to support others who might be newly diagnosed, or who might be experiencing greater difficulties. Another important function of a support group is that the members can concentrate on the things that they can do as opposed to the things that they can’t do. Support groups have proved popular for a number of health conditions and are at last being recognized by doctors as a necessary part of the complete management of an illness. Last, but not least, a theme which is emphasized throughout this book is that of the patient taking an active interest in the management of her/his condition. Support groups promote this sense of responsibility and self-reliance.
The following guidelines are based on three years’ experience of running a support group for patients with chronic stable angina, and hopefully will encourage more people to participate in a support group.
However, all support groups will be different because the people within them will be different, and each of the suggestions will have to be adapted to fit the group that you may be a member of.
Caution – group organizers at work!
One of the most important points about starting a support group of any kind, but particularly an angina support group, is to make sure that you, the organizers, have support! Having angina often means having to accept that you will have days where energy levels are low, so it is important to plan for these days and therefore reduce the frustration that this brings. If you intend to begin a support group, this will have to be considered and allowed for.
Forming a support group is tiring, often frustrating, sometimes hard work and time-consuming, but can be fun, very rewarding and gives some people a new lease of life. The advantages have to be weighed against the disadvantages before you begin; otherwise, if the group does not function well, the participants will experience having their hopes and expectations raised and then dashed and the organizers will experience a sense of failure.
*71/108/2*

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TREATING MIGRAINE WITHOUT DRUGS: MEDITATION AND YOGA
Meditation
The many different forms of meditation can be grouped into two general categories: those concerned with ‘emptying the mind’ and those in which internal thoughts are built up and maintained by an effort of concentration.
Transcendental meditation became very fashionable in the West during the 1960s and much is claimed for it by headache sufferers. It is not surprising that an act of relaxation or withdrawal from everyday activities is associated with relief of tension which produces a reduction in headache frequency. It is less likely to be effective once a headache has started, presumably because the metabolic changes which occur during the headache make it difficult to maintain the appropriate state of mind.
Yoga
Yoga is an ancient Indian technique of achieving total bodily and mental control in an attempt to reach new heights of awareness and in promoting relaxation. There have been several trials of yoga methods of meditation in the prevention of migraine and the results, although preliminary, are encouraging.
‘Yoga of the body’ is concerned with making the body a fit vehicle for the mind as it meditates. The first precepts of control are based on the type of foods ingested, and are similar to much of the dietary advice often given for migraine: no citrus fruits, little cheese, no alcohol or wine, no garlic or onions and, in addition, no smoking. Garlic and onions are excluded because they may cause gastric upset. Meals are taken three times a day, the stomach being ‘half filled with food, a quarter filled with water and one quarter left empty’, to avoid any feeling of fullness. Food has to be chewed thoroughly and eaten slowly (in contrast to the gulping of quick snack lunches seen in British pubs). Constipation is avoided by adding bran to the diet. Much of this advice is commonsense and it is understandable that, with this regime, the body will function in a better way.
The exercises of yoga are divided into those in which breathing is the main concern, and those which exercise the rest of the body. The breathing exercises are designed to establish conscious control over respiration as well as using the stomach muscles to ensure that the lungs are fully inflated.
The bodily exercises are performed very slowly and involve either stretching movements or the maintenance of particular positions for periods of time. Physiologically, the maintenance of posture utilizes the stretch reflex of muscles. The whole system can be likened to a cat stretching and rolling, with movements being slow and graceful. It is essential that these exercises become comfortable and patience is needed for this but, after three months’ practice, many patients find they feel much better, fitter, and much less likely to develop headaches.
There are many techniques of teaching yoga. The meditation aspect of yoga is the most important so that those techniques controlling thought, or holding thoughts in the mind and so building on them, are likely to be of benefit in developing control.
Current approaches involve combining certain yoga techniques with biofeedback and it will be interesting to see how much this will achieve; it is conceivable that migraine patients who practice these techniques will not be so much at the mercy of stress and therefore will suffer fewer headaches.
*46/152/5*

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Toradol (Ketorolac)
TREATING THE MUSCLE CONTRACTION HEADACHE: PART 2
Norgesic is a combination drug that contains orphenadrine (a muscle relaxant), aspirin, phenacetin, and caffeine.
Parafon Forte is another combination medication combining the muscle relaxant chlorzoxazone and acetaminophen.
Propoxyphene (Darvon) is a very popular analgesic used for a variety of painful conditions. This drug is chemically related to narcotics, and abuse and dependence, as well as withdrawal problems, develop if the drug is used over a long period of time. Darvon comes in a plain form and in combination with a variety of simple analgesics, including aspirin, phenacetin, and acetaminophen.
Codeine is a narcotic analgesic that can be added to a large number of simple analgesics. It is a fairly effective and relatively safe pain reliever but abuse commonly occurs, although not to the extent observed with more potent narcotic analgesics.
For patients with frequently recurring muscle contraction headaches, antidepressants seem to be the most effective drugs. Scientific observations, such as those by Dr. Donald Dalessio, a noted headache expert from La Jolla, California, have shown that the antidepressants, such as amitriptyline (Endep and Elavil), may be quite helpful in treating this disorder.
Other antidepressants of similar structure are also widely employed.
It is our opinion that for daily muscle contraction headaches these antidepressants are perhaps the most effective medications available. It is important to keep in mind that their benefit may have nothing to do with their effect as an antidepressant. In fact, patients who are not depressed will generally not experience any change in mood as a result of these drugs. Their benefit may be due to a mechanism that influences muscle contraction; drugs of similar structure are used as muscle relaxants. Additionally, there is some sparse evidence suggesting that these antidepressant medications may exert a primary effect on pain control centers and have been found useful in the treatment of diverse causes of chronic pain such as cancer, diabetes, and pain following certain types of infections.
It is not unusual in our experience for patients with daily pain to find themselves taking ten to twenty analgesic tablets each day, a quantity that is unquestionably hazardous to mind and body. Furthermore, relief of pain may require complete discontinuance of all analgesic medication, since, in a yet-to-be-defined way, regular use of analgesics may actually lower your pain threshold. It is often necessary to hospitalize patients to withdraw these medications safely and completely.
The preventive medications can be useful not only in providing some relief to the patient but also in helping to eliminate the harmful medications on which the patient may have become dependent. During this “plateau” of relief, it is important to work very hard to develop insight into the cause of the pain and to pursue non-medicinal interventions for long-term control.
It is for this and other reasons that recent research regarding biofeedback and muscle contraction is so important. A score of headache experts have shown impressive results using biofeedback and relaxation methods for treatment of recurring muscle contraction headaches. Dr. Lee Kudrow of Encino, California, one such headache authority, has actually found that patients undergoing biofeedback treatment for muscle contraction headaches who are able and willing to give up analgesics had better long-term results from the biofeedback treatment than patients who continued to use pain relievers along with the biofeedback therapy. Biofeedback is becoming the treatment of choice for muscle contraction headaches, particularly in young people.
We have found that, in addition to biofeedback and the cautious use of some medications, cervical collars for support and the maintenance of good posture, neck traction, and careful exercise of the neck muscles may be an effective way to treat many people.
The application of heat, regular massage, perhaps using a vibrator, and formal physical therapy can be very successful. Sleeping on a pillow that supports the neck and allows a slightly backward posture of the head may prove beneficial for some patients.
When emotional factors are crucial in the production of muscle contraction headaches, a trusting relationship with your physician is essential. The doctor must assist you to modify the circumstances in your life that may provoke your headaches. Muscle contraction headaches often develop or worsen at the same time that emotional burdens intensify.
It is essential to once again stress that if your doctor asks you to undergo a psychological evaluation to help identify areas of anger or hostility, to help modify certain situations in your life, to help you learn to express your feelings more openly, deal with stress less harmfully, or learn to relax, you should not resist or resent such recommendations. Those of us who see many patients in pain, particularly with muscle contraction headaches, have come to recognize, through many years of experience, that these interventions may play a dramatically effective role in bringing relief and a healthier life.
Chronic unrelenting stress must be recognized as a serious health hazard, and any legitimate effort to relieve it should be considered beneficial and wholesome.
An active, productive, and useful life, together with a feeling of self-reliance, is also beneficial. Good eating habits, regular exercise, adequate rest, and learning to relax and enjoy life’s pleasures are all important in the total headache treatment. This may mean restructuring the pattern of your life, or it may require only minimal but crucial modifications. In the end, your active participation in your own therapy, together with the advice and counseling of a concerned physician, is the essential ingredient in treating this troublesome headache disorder.
During the past several years, headache authorities have come to recognize that the mechanism of most chronic headaches, particularly those suffered daily, have both muscle contraction and vascular components. The history is characterized by daily occurring muscle contraction pain and periodic migraine or migrainelike headaches, approximately once every week or so. Many patients suffering from this disorder take excessive amounts of analgesics. Successful treatment often requires therapy directed at both muscular and vascular elements. Often nonmedicinal interventions such as biofeedback and psychotherapy may be necessary in addition to appropriate medications.
*46/88/2*

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PREVENTING BACK PAIN: WHAT ABOUT LIFTING?
Lifting does not have to be dangerous even when done regularly at work or at home. Know the facts about lifting so that you can protect your back from forces that increase the work it must do and, consequently, the chance of back pain and injury.
Did you know that very high forces are placed on the lower back when any of us lifts an object? Lifting an object weighing 86 pounds (39 kg), even with proper lifting techniques, cam cause a force of over 700 pounds on the lower back discs! Heavier weights cause proportionally higher loads on the lower back. In light of these facts, it is surprising that injuries and back pain are not more common than they are.
We can’t avoid many of our daily tasks, but we must become smart in the way we use our backs. The regular exercise program will continue to strengthen your back muscles. It makes sense that the stronger and more flexible the back muscles, the more they may be able to tolerate pressures. Proper lifting techniques can help minimize the forces we place on the back.
The following sections describe a few steps to keep in mind to help avoid back injuries when lifting. The National Institute for Occupational Safety and Health has given some of these recommendations for preventing injuries from lifting.
*46/135/5*

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Other names: Epitol, Carbatrol
Tegretol (Carbamazepine)
TREATING MIGRAINE WITHOUT DRUGS: PSYCHIATRIC TREATMENT AND BIOFEEDBACK
Psychiatric treatment
Many patients with migraine have some degree of depression but this may be secondary to their headaches rather than a primary cause. In these cases, the opinion of a psychiatrist is of great value since their training facilitates assessment of which patient will respond best to a particular method of therapy. Some experts favour a more complex interpretation of headaches based on psychoanalytic theory but this approach has not often proved helpful.
Biofeedback
Biofeedback is the term used for the methods by which conscious control can be gained of functions that are usually automatic. This is achieved by ‘feeding back’ to the patient information about the automatic function so that its control can be modified. Possibly the commonest use of biofeedback is in the control of blood pressure, where patients are told to concentrate in various ways and the results of their efforts are relayed to them; most people can learn a technique which will reduce their blood pressure, an effect which can be maintained. Epileptic patients often say ‘I almost had an attack but I felt it coming and fought it off-an interpretation of events verified using EEG monitoring; patients can be taught to suppress epileptic activity when the EEG information is fed back to them but the mechanism of this suppression is unknown.
There have been many attempts to treat migraine in the same way. Three types of information can be relayed to the migraine sufferer, the first of which is the degree of distension of the temporal artery. During an attack of migraine, the temporal artery becomes dilated and it is possible for sufferers to learn to reduce the diameter of the temporal artery, and so abort attacks.
Muscle contraction can also be brought under feedback control. When a patient develops a migraine associated with neck muscle tension, contraction of the neck can be recorded using a machine – the electromyograph (EMG). Therapy consists of feeding back to the patient information on the amount of muscle activity in the neck, so encouraging him to relax. Results have been fairly encouraging but there is a great placebo effect; the relief of tension can work by affecting the stress provoking the migraine attack, and other forms of relaxation not using biofeedback can also relieve the tension in the muscles of the neck.
Thirdly, there is an increase in temperature over the head during a migraine attack with an increase in blood flow; this is most marked during an attack of cluster headache. The response of blood vessels of the limbs to increased blood flow is abnormal in migraine sufferers, and increasing the blood flow through the skin of the hand is associated with a decreased flow of blood to the skin of the forehead. People can alter the blood flow through their hands following appropriate concentration using biofeedback and, interestingly enough, it is the dominant hand which shows the best response. Using biofeedback, the patient can be trained to warm his hand when an attack is coming on. This technique is not effective in all sufferers, however, because the responses of the blood vessels vary. (Similar responses to the same stimuli occur in anger: some people go white due to constriction of their blood vessels whilst others go red, due to dilation of their blood vessels.)
Hand-warming is worth trying as the biofeedback apparatus required is fairly simple, and consists of a surface thermometer attached to the hand with a means of relaying the information to the patient; these devices are becoming available commercially and are not too expensive. The patient sits in a relaxed position and attempts various thoughts in order to obtain vessel constriction until a satisfactory lessening in blood flow is obtained, as evidenced by a small decrease in temperature. It is the skin temperature that is important so there is no point in clenching the hand. With practice, when the technique has been mastered, changes in temperature of one to two degrees can be achieved.
Anecdotal reports bear out the usefulness of the method: one patient, who suffered from severe cluster headaches, spontaneously said ‘I know it sounds funny, but I think that if I concentrate I can make my hand feel warmer and then the pain in my head seems to get better.’
*45/152/5*

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TREATING THE MUSCLE CONTRACTION HEADACHE: PART 1
The basic elements of treatment for muscle contraction headaches include reassurance, the establishment of a trusting relationship between the patient and the doctor, the removal of physical or emotional triggering factors, and treatment of the discomfort. This is not very different from what has been suggested as the treatment for migraine.
If a physical illness is present, that abnormality must be treated appropriately. If no physical abnormalities can be found to account for the headaches, it is often assumed that emotions play a critical role in the production of the headaches. This presumption should not be made prematurely, since emotional upset usually accompanies or follows any prolonged and painful event. Simply suffering from a regular and sometimes daily pain is enough to cause the
“pain-distress” cycle in which pain triggers the emotional upset and the emotional upset triggers the pain. It is, therefore, very important not to simply assume that emotion is the cause of the muscle contraction headaches, even though features of emotional upset may be present.
To interrupt and stop the pain-distress cycle and to alleviate the pain, it is often necessary to use combinations of analgesics, muscle relaxants, tranquilizers, and antidepressants. The use of these medications, particularly analgesics and tranquilizers, must be temporary. Regular and continued use of many of these drugs is potentially harmful to your body. Prolonged use of drugs encourages the development of emotional as well as physical dependence.
There seems to be a strong tendency for patients with recurring muscle contraction headaches to abusively use pain-relieving and tranquilizing medication. Not only does this have physical consequences, such as injuring the stomach, liver, and kidneys, but this abuse actually promotes headaches and physical and emotional dependence on these agents. The antidepressants (see below) may be appropriate for somewhat longer periods of time in certain situations, but indefinite reliance on any medication, including these, must be considered a failure of the overall headache treatment program.
A wide variety of analgesics can be used to treat the occasional muscle contraction headache. Aspirin and acetaminophen (Tylenol and Datril) are relatively safe and often very helpful.
Combination drugs are widely used although many doctors tend to avoid their use whenever possible.
Fiorinal is a combination brand-name drug, available in cheaper generic versions, that combines a barbiturate sedative, aspirin, phenacetin (a simple but potentially dangerous analgesic), and caffeine. Phenacetin, while an effective analgesic, can, like some other analgesics, injure the kidneys if there is prolonged and regular use. This combination product is popular and effective in many circumstances, but is so frequently abused that we generally
discourage its use except occasionally.
In Canada, phenacetin has been removed from all combination drug products containing salicylates (such as aspirin). In the United States, phenacetin is still available in prescription drugs (not in over-the-counter products), but it is likely that phenacetin will soon be removed from such prescription drugs in the United States as well.
*45/88/2*

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PREVENTING BACK PAIN: PROTECT BACK WHILE STANDING AND SLEEPING
Standing
When you stand or walk, remember that when the spine is bent over even a little, the pressures on the lower back increase. You place the least pressure on your back when you are in a standing position with your back fairly straight. You don’t need to have perfect posture, but thinking about your back a little can bring great rewards.
If your daily activity involves much standing, wear comfortable shoes that have good support. Try to avoid higher heels. A lightweight athletic shoe is a good choice.
Avoid standing in one position for long periods at a time. You might try placing a rubber mat in the area if you must stand for long periods. The mat will give some cushioning to your feet and back.
When you stand, you can occasionally rest or “prop” one foot on a box or stool for comfort.
Hold your abdominal muscles in. Avoid the “swayback” position, which puts higher pressures on the back.
Sleeping
Use a firm mattress on your bed for good support. If your mattress is too soft, it may put extra stress on your back. Remember that mattresses don’t last forever. If your mattress is more than five years old, it may need to be replaced. Some people find the most relief for back pain when they sleep on a water bed.
For sleeping, choose the position that is most comfortable. If your neck or upper back is painful, pillows made to fit the contour of the neck are available. You may want to try one of these, although their results for relief of pain vary with individuals.
For people who have arthritis in the back, it is usually a good idea to try to spend some part of the sleep hours lying on the stomach. This may help with posture, especially in prevention of a stooped-over posture.
As your muscles become stronger with the regular exercise program (usually after a few weeks to a few months), your posture will improve without your thinking about it. Adding these simple measures to protect your back from unnecessary forces will give you even better results.
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TREATING MIGRAINE WITHOUT DRUGS: AVOIDANCE OF STRESS
Although a certain amount of stress is a normal part of human existence, excessive amounts can undoubtedly act as a provocative factor. In many patients it therefore seems logical to try to lessen this, if possible. The first step, which often helps greatly, is to remove any worries regarding the nature of migraine with an explanation as well as reassurance that there is nothing more seriously wrong. Only very rarely are worries about the nature of the illness sufficiently intractable to need referral to a psychiatrist.
Although life-style cannot always be changed, the worsening of any stress disease indicates the need for its re-examination. Obvious examples include the person in business or one of the professions who never takes time off to relax; here the important point to emphasize is that one headache a month equals one day lost from work a month, so that it is a good investment to take some time off. The type ‘A’ person may find periods of relaxation which take the form of just staring at the ceiling punitive; in this sort of case, physical exercise may be indicated, starting gently in those unaccustomed to it.
Although it is impractical to suggest that the hard-working businessman gives up his job, it is possible to help him cope with the pressures involved in his work. By preventing the physiological (e.g. hormonal) changes caused by stress, the cycle of chemical changes involved in migraine can be arrested. One useful method of achieving this is relaxation therapy where many of the changes induced are the reverse of those seen in the tension headache/migraine syndrome. During relaxation certain physiological changes occur, e.g. muscle tone is decreased, and respiration and the heart rate slow; all of these are manifestations of a decrease in the tone of sympathetic muscles. Historically, there have been numerous types of relaxation therapy: the Japanese communal bath, which is not used for cleansing purposes, the Finnish sauna, the American ‘whirlpool’, and massage are all attempts in this direction. There is some evidence that teaching a tense person to relax is of benefit in reducing the incidence of headaches but it is difficult to separate this improvement from the placebo response, so that the claims to success of relaxation therapy are difficult to interpret.
Often those persons who most need relaxation find the greatest difficulty in obtaining it. One way recommended for assessing a person’s state of tension is to imitate his posture, e.g. sitting on the edge of the chair leaning forward with shoulders hunched and fists clenched. If the patient holds this posture for a few minutes, there will be a feeling of discomfort. If, on breathing out rapidly there is a smooth exhalation, relaxation is possible but interrupted breathing with an involuntary holding of the breath implies that the patient may be resistant to relaxation therapy.
Relaxation therapy aims at providing a variety of positive steps to ensure that the last remains of tension have been removed. Relaxation is much easier in a warm quiet room. Many hospitals and therapists have their own techniques for relaxation.
*44/152/5*

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DIAGNOSING THE MUSCLE CONTRACTION HEADACHE
The diagnosis of muscle contraction headache, like that of migraine, is based heavily on noting the characteristic special symptoms of the headache and finding out exactly what activates the headache’s occurrence. A thorough physical examination is necessary, and during the examination, special attention must be given to the areas from which the pain seems to come. A careful manual search for sensitive points must be carried out. Cautious bending forward and bending backward, along with rotation of the head in a variety of positions, can sometimes point up the positions that provoke pain. Spasm and contraction of the neck muscles can occasionally be felt, but between attacks the muscles may feel normal.
X rays of the skull and neck are often performed to determine whether there is any evidence of bone abnormalities. The jaw and the jaw joint must be evaluated as well. The muscles, nerves, and spinal cord and other soft tissues cannot be evaluated effectively by routine X rays, which show only bone or tissue containing calcium. A manual examination of the head and neck should not be neglected simply because X rays are ordered.
Invasive diagnostic tests, the type that enter the body and cause risks, are generally not required unless important abnormalities are spotted during the X ray or the manual examinations. You and your doctor must recognize that the presence of muscle contraction means that there is a possibility that a specific disease is responsible for the contraction, and this must be considered in the evaluation.
Likewise, it is very important in some patients to look for relevant emotional distress. While many of our patients are offended if we raise the possibility, you should be receptive to a psychological interview to determine if, in fact, there are elements of anger, depression, rage, or other issues that are known to be present in many patients with muscle contraction headaches. It is our opinion that as long as your doctor shows an open-minded attitude towards all possible factors, not just emotional ones, you should not resist an inquiry into the emotional elements that could be important in creating your headache cycle.
*44/88/2*

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Relafen (Nabumetone)
MIGRAINE TREATMENT: STRESS AS PROVOCATIVE FACTOR
Stress can undoubtedly act as a provocative factor in many patients and a logical form of treatment is to lessen this, if possible.
Frustrating situations are met with in nearly all walks of life. One patient told his story as follows:
From the standpoint of migraine, the year beginning 1 July was noteworthy because of the infrequency and mildness of attacks; during this period the amount of work in which I had been engaged just filled each day, making it possible to maintain certain personal ideals of perfection. Since November the greatest amount of concentration has been directed to quantitative determinations in a large number of microscopic sections of tissues. Frequent short periods of this rather monotonous work during almost every day had not been unpleasant. On 4 February it was suggested that an attempt be made to complete this research sufficiently to present an abstract of the work to a scientific society within 16 days for consideration as a presentation at a later date. Accepting this suggestion I therefore increased my concentration on this problem by working in the evenings. It soon became evident that the amount of work accomplished was falling far short of any schedule that would produce a sufficient number of figures within this time, and furthermore, the work was for the first time becoming distasteful. In the night, after the second evening in the laboratory I was awakened by an ache over the right eye associated with nausea. After a period of semi-wakefulness, sleep was resumed and the next day the only trace of a headache was pain on the right side of the head on coughing. After the third evening of laboratory work I was awakened at 4 a.m. by an ache over the left eye associated with nausea. Unlike the symptoms of the previous night they rapidly increased in severity until it became necessary to get in a hot bath to secure some relief. When I returned to bed, the pain and nausea resumed their former severity and 1 gram of codeine finally relieved their symptoms and allowed a few hours of sleep. During the entire next day there were nausea and a constant severe generalized headache extending downward into the back of the neck, which was made worse by walking, talking or reaching. The following morning the symptoms had vanished.
This story will strike a chord with almost every migraine sufferer. Although it is possible to explain this sort of tension on a biochemical basis, too few studies have been done in chronic stress situations to pinpoint the problem but the existence of two different personality types is pertinent. Type ‘B’ people who thrive on challenges get a ‘charge or kick’ by being active and doing things and may in fact be depressed and lethargic when under-stimulated; with this personality, absence of stress may spark off headaches. The patient above is an example of a Type ‘A’ personality, who reacted badly to stress.
*43/152/5*

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Other names: Benemid
Probalan (Probenecid)
PREVENTING BACK PAIN: WEIGHT CONTROL AND CONDITIONING EXERCISE
Control Your Weight
Extra body weight puts additional stress on the spine, the muscles, and the other soft tissues in the back. It makes sense that losing your extra pounds would lower the work load on your back. You don’t have to be at your exact ideal body weight, but the closer you can get, the better your back should respond.
If you are overweight, begin a slow but steady weight loss program. A loss of only one pound a week is an excellent goal. This rate of weight loss may not sound fast enough, but it adds up to 52 pounds in one year. If you lose at this slow and steady rate, your chances of keeping the weight off are much higher.
Add a Conditioning Exercise
The easiest way to do a conditioning exercise is to add a simple walking program to your daily schedule. Pick a short distance and walk it daily. You may be able to set a regular time for your walking each day, or, if necessary, move the time around according to your schedule. Just be sure that you gradually increase the distance you walk daily. You will be surprised at how quickly you’ll be able to see progress.
Whatever conditioning exercise you choose, it should be convenient and one you don’t mind doing. If you don’t enjoy walking, try bicycle riding, an exercise bike, swimming, or some other exercise you enjoy. Many of our patients prefer to have an exercise bike or treadmill in their home so that they can exercise anytime, day or night, at their convenience. There is no threat to safety, no problem from bad weather, and no excuse for not exercising when the equipment is available at home.
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Pletal (Cilostazol)
MIGRAINE: TREATMENT WITHOUT DRUGS
There is no drug, not even aspirin that does not have side-effects. It has been estimated that nearly one-third of all illnesses are iatrogenic, i.e. due to drugs. For this reason, most sufferers would prefer to do without drugs if possible. There are two main approaches to therapy: first, prevention and, second, treatment of the symptoms as soon as they occur. The majority of sufferers from migraine does not go to their doctor and will only do so if the frequency of the headaches suddenly increases. This increase may be due either to an alteration in life circumstances, e.g. increasing stress, or increased exposure to particular precipitants. There may also be a combination of the two, for example, when someone whose headaches are made worse by tobacco smokes more under stress; the combination of these two factors, smoking and stress, is likely to aggravate migraine more than either one singly.
The placebo response
The word placebo means T will please’. It is used to describe a response found with many illnesses including, surprisingly, serious ones, namely the tendency of the patient to get better on treatment which theoretically should have no effect at all. Because the patient believes that the treatment is helping, he is helped because symptoms disappear; indeed occasionally ‘physical’ (organic) lesions have been known to diminish, showing the close relationship between the mind and body. Some types of faith-healing probably work in this way, fortifying the patient, boosting confidence that something is being done, and increasing the body’s recuperative powers. There is no doubt that the psychological status of a person affects many of the body’s mechanisms.
The placebo response is influenced to a great extent by the attitudes and personality of the attending therapist and this is illustrated by the two following cases:
A 30-year-old housewife had headaches of increasing frequency and intensity. Her 4 1/2-?ear-old daughter was suffering from feeding problems and the woman was becoming increasingly frustrated and angry so that at times she assaulted the child physically. During her first clinic visit the woman confessed her problems to a friendly and sympathetic physician and, by the end of the interview, was much relieved. A remission from headaches of several weeks followed. At her next visit the physician adopted a stern and critical attitude and, ten minutes later, she began to have a severe migraine which responded to the injection of ergotamine.
A 44-year-old woman had frequent migraine attacks. She was given a box of placebo pills with words of kindness, reassurance, and indications of extreme interest. It was also emphasized that she had no serious structural defect or tumour, and she left the clinic feeling relaxed and secure. For six weeks following the interview she was headache-free, but gradually the condition began to creep back.
This case history exemplifies a characteristic of migraine. It is quite common for a migraine sufferer to respond very well initially to any new therapeutic regime, but it is nearly as common for the headaches to return subsequently as badly as ever. The explanation is that the initial placebo response wears off and indicates that the treatment has had no specific effect of its own. Another interesting feature is the amazing variety of totally different drugs which seem to be effective in the treatment of migraine. It is for this reason that claims of success for a particular form of treatment have to be carefully analyzed. The more attention and interest a patient gets, the greater the placebo effect will be. To some extent this may explain the good effect of certain dietary treatment or, indeed, any treatment in which the patient obtains a good deal of attention.
*42/152/5*

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WHAT TRIGGERS THE SPASM: POSTURE OR PROLONGED USE OF MUSCLES
If you hold your head and neck rigid or in an awkward position for a long period of time, muscle pain may develop. This is common in persons who become tense while driving their automobiles in bad weather or heavy traffic. Bedtime television watchers may provoke this discomfort by slouching in bed with the head propped forward by a pillow as they peer at the television set located at the foot of the bed. Looking down while reading may also lead to muscle contraction pain. This chin-on-chest posture is apt to be particularly uncomfortable for anyone who has a preexisting arthritis in the neck. Prolonged extension of the neck upward and backward, as when painting a ceiling, can, of course, also be painful.
One of our patients noted that she suffered headaches only on the evenings that she played cards with friends. The headache would usually begin late in the evening, after she had spent many hours looking down at the cards she held in her hands. Concentrating on the cards and enduring the smoke in the room cannot be entirely overlooked as contributing factors, but it eventually became clear that the woman’s chin-on-chest posture was to a large extent responsible for producing the discomfort. She was given a cervical collar to wear during her card parties. This device is worn around the neck and assists in supporting the head and limits the forward movement of the head and neck. To the patient’s delight, and to ours as well, her headaches lessened, and the pain did not interfere with her enjoyment of the game.
The chin-on-chest posture often produces discomfort in those of you whose work or other activities require this position for long periods. Typing, reading, propping a telephone receiver between the shoulder and head while talking, and similar activities can cause headaches in some people.
Facial mannerisms, such as prolonged frowning, squinting, jaw clenching, gum chewing, teeth gnashing, even holding a smile or other movements of the face requiring specific muscle activity, may also provoke muscle pain that is felt as a headache. If you have arthritis of the jaw joint, imbalances, or other abnomalities of your jaw, the muscles around your jaw and temple area may painfully contract when the jaw is used, particularly during prolonged or intense chewing activity. This is often felt as a headache in the ear area or temple region.
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WHAT TRIGGERS THE SPASM: DISEASE OF THE NECK OR PAIN ELSEWHERE IN THE BODY
Pain from abnormalities of the neck, eyes, teeth, jaw, or anywhere else in the body may incite muscle contraction of the head, neck, or face muscles.
Muscle contraction headaches frequently accompany cervical arthritis (arthritis of the neck). Arthritis is an inflammation of the joints, and this process may affect almost any joint in the body. There are many types of arthritis, but the two most common are called osteoarthritis (osteo-means bone) and rheumatoid arthritis. Rheumatoid arthritis is the most serious but fortunately the least common of the two. It is a disorder that may begin at any age and cause
deformities of bone, frequently leading to crippling disabilities. Rheumatoid arthritis affects both young and old.
Osteoarthritis, also called degenerative arthritis, is by far the most common form of arthritis. This disorder eventually appears, to some extent, in almost everyone. It can affect nearly all joints of the body and is probably the result of years of physical stress on the joints. It can happen at any age but is most common after middle age. Most men and women over the age of forty-five show some evidence of osteoarthritis, but it can develop without apparent cause in younger people. Osteoarthritis causes pain on any movement of the involved joints, and it occasionally produces disability. When osteoarthritis affects the neck, the likelihood of developing muscle contraction headaches is increased. In part, this may be due to an automatic response of the muscles to “splint” the damaged bones against harmful movement, or the muscle contraction may be a response to the pain.
The arthritis can be severe or located in a critical spot. When this happens, portions of the degenerating bone can press on nerves and cause pain as well as neurological impairment. This process is referred to as a “pinched nerve” because the nerve becomes compressed, irritated, and subsequently inflamed. When the nerve is compressed, either by arthritis or by a vertebral disc (the “cushion” separating the vertebrae), pain, tingling, numbness, and weakness may develop. When the compression involves the nerves going to the arms or legs, the pains are often referred down the entire arm or leg. When the upper cervical nerves are involved, the pain from those nerves and the muscle contraction that is triggered by the pain may be referred up the back of the head.
Abnormalities of the neck, other than arthritis, can also trigger muscle contraction headaches. Injuries of the neck, such as whiplash, tumors of the spine, or congenital (present at birth)
deformities of the vertebrae or skull may result in pain and associated muscle contraction, which causes even more pain.
It seems that when any disease of the neck is present, muscle contraction headaches may be more easily triggered by emotional events than if the abnormality in the neck did not exist. In other words, abnormal conditions of the structures around the head and neck make it more likely for muscles of that region to painfully contract as a result of emotional factors, or any other triggering influences for that matter.
As we have already suggested, it is not uncommon for people with migraine to occasionally experience muscle contraction headaches at the same time they are suffering from a severe
migraine attack. Perhaps this is due to an unconscious attempt to hold the painful, throbbing head and neck immobile, since movement during the migraine attack is often nauseating and quite painful. Another explanation, however, is that pain from the migraine serves as a triggering stimulus for automatic muscle contraction.
*42/88/2*

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PREVENTING BACK PAIN: DON’T STOP THE EXERCISES
People with back pain frequently ask, “Once the pain is gone or much improved after one or two weeks, can anything be done to prevent the attacks?” Although the causes of the most common type of acute back pain are not known, and there is no absolute cure, there are steps you can take to make the attacks come less often, last a shorter time, and be less severe.
The prevention measures do not require a drastic life-style change. Most people are able to incorporate the program of exercise, weight control, body conditioning, and proper diet into their daily schedules without much difficulty. Most of our patients report that these measures intended to prevent their back pain actually enhance their overall well-being. They feel stronger, look healthier, and have more energy.
When the pain improves, don’t stop the exercise program. Remember that it takes weeks to months to build stronger muscles. You can make your back muscles stronger and more flexible, but it takes time. The exercise program may be the most important step available to you for prevention of future back pain.
Remember how painful the back pain was. Remind yourself that a regular back exercise program can help decrease the chance of that pain returning.
Finding the time to do the exercises may seem more difficult than performing them, but once you learn the exercises and their sequence becomes routine, you will be surprised to see that they can be done in a few minutes each day. Some of our patients tell us that they “can do without” the exercises because they are active during the day at work and other activities. There is a difference between activity and exercise. It is no coincidence that our busiest patients are also those with the worst back pain. In most cases, daily activities do not strengthen the back muscles and may actually increase the stress on them and the amount of work they must perform. For example, sitting at a desk and leaning slightly forward puts a large amount of constant pressure on the bones and discs of the lower back, creating more stress on the back muscles.
There is no replacement for making your back muscles stronger and more flexible. You might find the time for exercises by awakening a few minutes early, or doing the exercises at the end of your evening, or setting aside a few minutes during the day. Some people prefer to do all the exercises at one session each day, rather than twice daily. The important point is to do them regularly.
Our patients find that the exercises become much easier after a few weeks, and the results they see even in that short time make the effort worthwhile. Find a way to insert the exercises into your daily routine. Once you maintain a regular program for a few months, it will become unnatural not to do them.
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INVESTIGATIONS OF HEADACHES: BRAIN SCANNING
In certain cases of headache, a brain scan, of which there are two types, may need to be done. One type relies on the uptake of a radioactive isotope by abnormal tissue, such as a tumour. The patient is given an injection of a short-lived radioactive isotope into an arm vein from where it enters the arterial system and goes through the brain, ascending via the carotid arteries. By using a camera the isotope is followed up the carotid arteries to each cerebral hemisphere, where the radioactivity is then ‘washed out’. The flow of the isotope through the brain helps to distinguish between a tumour, which has a relatively high flow, and a stroke in which case the flow is very low. It is a quick and easy test to do but is not available in every hospital.
The other type of scanning is also quick and easy but is even less readily available, although it has revolutionized diagnosis. Computerized axial tomographic (CT or CAT) scanning examines ’slices’ of brain by moving the X-ray machine in such a way that the slice is motionless relative to the areas in front of, and behind, it. The moving areas become blurred while the ’slice’ – the area to be examined – retains its sharpness and is defined more clearly. The CT technique depends on the fact that different tissues absorb different amounts of radiation so that it is then easy to identify the different structures to see if there is any abnormality. Its precise place in migraine is still controversial but some reports suggest that in very severe cases there may be evidence of persistent brain changes.
These investigations carry no risk and are performed without fear of complication. Rarely, other X-ray techniques, which rely on the introduction of substances opaque to X-ray into either blood vessels (arteriography) or the subarachnoid space (air encephalography), have to be done in order to define the structures more clearly on X-ray films. These tests are often done under a general anesthetic.
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WHAT TRIGGERS THE SPASM: EMOTION
The following are only some of the events that can trigger muscle contraction headaches. Many of these headaches happen without any recognizable provoking factor.
Emotion?Prolonged worry, fear, depression, or internalized anger are all capable of causing the muscle contraction headache. A number of years ago, Dr. John R. Graham of Boston, a noted headache expert, compared the action of neck, scalp, and head muscles during emotionally disturbing events in humans and certain instinctive and automatic reflexes in animals threatened with danger. The neck and head muscles in the turtle, for example, automatically retract and pull the head under the protective cover of the shell. The ape also retracts its head into the well of the surrounding shoulders as the beast assumes the fighting posture. The similarity between this automatic response of lower animals and the automatic contraction of head and neck muscles in the human under stress raises the very interesting possibility that the automatic contraction of human neck and head muscles during emotional distress or danger represents a remnant of an automatic protective response in lower animals. In other words, the muscles of the head and neck contract in the presence of pain of the mind, just as the muscles of the arm respond to pain of a
broken bone. Perhaps the body is trying to pull the head under a shell that does not exist, and in a skeleton composed of bones that cannot retract, as is the case with the lower animals. When we tell some of our patients that if they were turtles their head would be under the shell all or most of the time, they laugh approvingly, acknowledging their distress and the imagined relief at having some place to hide.
We know that stress, frustration, and depression are common elements in the personality of those who suffer from muscle contraction headaches, even though the presence of these strong feelings may not be recognized on a conscious level. You might ask yourself if your expression is always very serious, or if you have a frown on your face even when relaxing. Do you often clench your fists or jaw, perspire without apparent cause, gnash your teeth, or frequently seem worried or preoccupied with one problem or another? Do you have a hard time relaxing? Do you continually find fault with people and events around you? Do you have a problem relating to your mother or father, husband, wife, or partner? Do you feel anger for these people on the one hand and love on the other? Are you able to express these feelings openly or even accept them without guilt?
Your muscle contraction headaches may have no relationship to emotional stress. It is likely, however, that many sufferers from muscle contraction headaches do indeed trigger these headaches through a variety of emotional factors.
Some headache researchers believe that many muscle contraction headaches may occur in the morning hours because during sleep very emotionally distressful events come to the surface of our conscience. Jaw clenching, poor neck posture, and arthritis may also be important factors in provoking morning muscle contraction headaches. While sleep should be relaxing and restful, for many people with muscle contraction headaches sleeping is the most physically and emotionally distressful time of their day, because it is during this time that the mind expresses itself without restraint, and the body reacts appropriately.
Dr. Seymour Diamond of Chicago, a well-known headache authority, has coined the term “depression headache” to describe the morning headache affecting patients with continuing depression.
*41/88/2*

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