Aricept (Donepezil Hcl)


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Aricept (Donepezil Hcl)
CENTRAL NERVOUS SYSTEM: BRAIN
In most animals the larger part of the brain is devoted to handling the physical functions of the body. In man the bulk of it is for the associations which give us memory and imagination and the ability to think, however poorly many of us seem to do it. I do not see how I can do better than compare it with a telephone exchange, which instead of having thousands of subscribers, has possibly millions of wires and switches, making communications practically infinite in number. The front part of our brain, called the cerebrum, is the site for these latter activities. Hence the higher foreheads of men.
The brain is a good deal of a luxury, the spinal cord taking care of most of the functions necessary for life. But after one has had luxuries long enough, they may develop into necessities; witness the automobile. A frog which has had its brain removed may live in almost a normal manner. Old-fashioned boys on a farm knew that a hen with its head cut off would scurry about for some time. But the unfortunate French aristocrats in the Reign of Terror never moved after the knife of the guillotine had fallen.
Man has an enormous brain. We are told that elephants and whales are the only animals which possess larger ones; and are not those brains minute compared to their owners’ size? But size alone does not distinguish man’s brain. He has many more convolutions, or folds, of the surface of the brain. This, you can see, increases the area of the surface, and it is this surface or cortex which is supposed to be the most highly developed part. The fissures between these folds have been studied, charted, and named. The biggest and best known is the fissure of Rolando. Along this, one on each side of the brain, are the parts which control the muscular movements of the opposite side of the body.
Besides these “motor areas” which control the muscular motions of definite parts of the body there are other areas for sight, smell, hearing, and sensations from the different parts of the skin. Also there are certain areas, injury to which produces aphasia, which literally means lack of speech, although there are at times other manifestations, such as agraphia, or inability to write the desired letters. Thus Dr. Samuel Johnson had a paralytic stroke which he described graphically soon after, demonstrating that his aphasia was not an impairment of the intellect. “My speech was taken from me. I made a Latin prayer in verse. The lines were not good but I knew them not to be good. In penning a note I had some difficulty; my hand, I knew not how or why, made wrong letters.”
After reading this, do not be disturbed because recently when attempting to introduce your friend Jones you were unable to pronounce his name. That was due to embarrassment and nervousness, not to a lesion in any brain center.
The detailed knowledge of all these specialized areas in the cerebrum, or front part of the brain, has been accumulated over many years. In the Franco-Prussian War of 1870, surgeons, operating upon a wounded soldier, noted that when they stimulated with a weak electrical current a spot on the side of the brain, a definite localized muscular response occurred on the other side of the body. Naturally this discovery has been followed up through the years until a lot is now known. Reversing the problem, if certain muscles are paralyzed, the physician may thus get a strong hint as to what part of the brain he should investigate for trouble.
*44/276/5*

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