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REMOTE CONTROLS: VITAMINS
Most of the human body can be seen and studied by the skilled observer with his microscope. But we now come to consider some infinitesimal parts of us, mysterious but so important that they have been discovered chiefly by our startling, sometimes dire symptoms when these tiniest parts are absent or do not function properly. We are a long way now from the times when people believed only what they saw. We can be much more definite and certain than in those days, for any amateur magician knows that the motion of the hand is quicker than the eye, and a legally trained man will tell you that proper circumstantial evidence is more reliable than the testimony of witnesses as to what they saw.
Although the players in this game about to be described are little, they are clever and they have the fighting spirit. Their team-play would make the Notre Dame squad look like a bunch of sandlot scrubs. We can tell you a lot about their background, what they did in past seasons, and can outline many of their most brilliant plays.
Sir William M. Bayliss in his book on physiology stressed the fact that there are many chemical compounds which are indispensable to the normal activities of organisms, although present in only infinitesimal amounts. He was talking about hormones. Since his day the study of these, along with vitamins and enzymes, has shown that these littlest things are more important even than he surmised. Perhaps it would be well to tell what these three substances are before we consider their activities. A hormone is a chemical substance formed in one organ, and carried by the blood to other organs or tissues on which they act. They have been called “chemical messengers.” An enzyme is a complex organic chemical, produced by living cells, which by its presence brings about certain chemical changes – as for example, pepsin, which is produced by cells of the mucous membrane of the stomach. What vitamins are and how they act will be considered in the following pages.
For instance, we are told that Dr. Edward ? Kendall, when he first isolated thyroxin, which is the material that does the work of the thyroid, used six thousand pounds of thyroid tissue in order to get one ounce of thyroxin. Yet, compared with some of the minute amounts that are dealt with nowadays, Dr. Kendall collected an enormous lot. We talk nowadays of milligrams. A milligram is a thousandth of a gram or one thirty-thousandth of an ounce, and I have before me a statement that one man got ten milligrams of male hormones out of seventy-two million milligrams of urine. It seems evident now that a vitamin molecule is part of an enzyme molecule; yet it is believed that a single cell of the body, which is so small that it can be seen only under a microscope, may have many enzymes in it. Some of the metals are also used in minute amounts. It has recently been determined that there has to be some cobalt in order to form vitamin B12.
Enzymes seem to be the ultimate agents which do things in the body. We have long talked about the enzymes which digest our food. It has been pretty certainly determined that there are such definite substances, for we know where and how they work. Physiologists feel sure from their observations that there are innumerable numbers of such enzymes throughout the body. In fact wherever there is life, in or out of the animal body, there are enzymes present. One of the busiest enzymes that you are all familiar with is the enzyme which causes the fermentation of sugars and produces alcohol. Vitamins are necessary to make these enzymes, and hormones seem to be necessary to regulate the work of enzymes in the body.
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