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GENES AND DNA
Give a scientist two drops of blood, one from a man and one from a boy, and the scientist soon can tell you, with 99.999 percent certainty, if the man is the true father of the boy.
With the same precision, scientists can take a spot of blood or semen or a hair root from the scene of a crime and tell you whether those samples match others taken from an accused person. Even a few skin cells from under the fingernails of a murder victim can lead police to the killer.
All this is possible because, in 1985, the British biologist Alec Jeffreys invented DNA fingerprinting, a revolutionary system for identifying humans and animals. This method is fast being viewed as the major addition to the field of criminal and civil justice in a full generation of forensic science.
(Anybody who watched the O. J. Simpson trial for even a half day realizes that DNA fingerprinting has come of age.)
DNA is a complex chemical that carries all the information that your body needs to build a complete organism from the moment of conception when sperm and egg meet. Each of us inherited DNA from our parents, and they from their parents. No two people, not even identical twins, have identical DNA. Science has shown how to compare DNA taken from one person with the DNA of another. Like fingerprints, an individual’s DNA has no identical counterpart.
Ever since it was first used for crime detection by the British police in 1987, law enforcement officials worldwide have been pushing to implement the technique in their own operations. Says Paul Ferrara, director of the Division of Forensic Science for the State of Virginia: “Hundreds, if not thousands, of cases have been solved with this technology.”
Despite its name, the method has nothing to do with fingerprints. Both DNA samples and actual fingerprints can identify a particular person with few vestiges of doubt. With DNA fingerprinting-by using samples of your hair, blood, or other cells – scientists can pick you out of a crowd with such accuracy that the odds are a million to one in their favor. Similarly, they can single out a criminal who leaves the tiniest personal trace at the scene of a crime.
Just 2 years after Dr. Jeffreys made his discovery at the University of Leicester in England; he applied his DNA fingerprinting method and proved that a man suspected of murder and rape was innocent: DNA from the suspect’s blood did not match the DNA from semen stains found on the victims, two 15-year-old girls.
Police tracked down the true criminal by asking for blood samples from 5,512 men in the neighborhood in which the crimes had been committed. One of the men, Colin Pitchfork, drew police attention by asking a friend to give blood in his stead. After he was arrested, Mr. Pitchfork’s blood sample was taken. His DNA matched that of the semen stains.
“I was enormously surprised by the Pitchfork case,” Dr. Jeffreys recalls. “When the police approached me, I told them I doubted whether it would work. I was wrong. Had the man not been caught, he would have killed again.”
The technique is intricate and requires several chemical steps. In the final step, a “print” is represented as a series of horizontal bars resembling the bar codes imprinted on packaged goods sold in supermarkets.
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